Amazon Prime Day Deals: Up to 68% Off Serums and Moisturizers
Julianne Bellew is a digital creator covering beauty, makeup, kitchen, baking, and cooking. She enjoys discovering useful products, everyday favorites, and worthwhile deals that help readers shop smarter for their beauty routines and kitchens.
Article summary
Skincare is the category Koupon shoppers actually buy — these ten moved 117,000 units between them last month. Verified 26 September 2026, up to 68% off, with nine of the ten under $32 and no codes needed.
Amazon Prime Day Deals: Up to 68% Off Serums and Moisturizers
Koupon.ai has verified amazon prime day deals across skincare ahead of Prime Big Deal Days, led by the medicube Exosome Shot Zero ampoule at $12.34 — 68% off its $39 list price, checked 26 September 2026. This is the category people on Koupon actually buy: the ten amazon prime day deals below sold 117,000 units between them last month, and nine of the ten are under $32.
Amazon prime day deals: the serums people actually buy:
Ranked by units sold last month, not by discount. Serums are where the active ingredients live, so this is the part of a routine worth spending on — more in beauty deals.
CeraVe Skin Brightening Vitamin C Serum — $20.65, 29% off:
The best seller on this page by a distance — 20,000 units last month — down from $28.99. CeraVe is the brand dermatologists actually name, and this is their vitamin C with ceramides rather than the stripped-down version.
medicube Exosome Shot Zero 2,000 PPM ampoule — $12.34, 68% off:
The deepest cut here, down from $39. K-beauty exosome ampoules normally sit well above $30, so under thirteen dollars is the reason 10,000 people bought it.
Eclat Vitamin C Serum — $9.99, 47% off:
Under ten dollars, down from $18.99. The cheapest way to try vitamin C before committing to the CeraVe or La Roche-Posay versions above and below.
La Roche-Posay 12% Vitamin C Face Serum — $31.71, 30% off:
Down from $44.99. Twelve percent is a serious concentration — this is the clinical end of the category, and it rarely drops below $35.
La Roche-Posay Retinol Face Serum with Niacinamide — $31.72, 29% off:
$31.72 from $44.99. Pairs with the vitamin C above — use one in the morning and one at night, not both at once.
Moisturizers and creams under $21:
The other half of a routine, and the half people underspend on. Everything in this section is under $21 — see the rest in trending beauty deals.
celimax The Vita-A Retinal Shot — $20.24, 33% off:
Down from $30. Retinal rather than retinol — it converts faster on skin, which is why it costs more per bottle than the drugstore versions.
CeraVe Oil Control Gel-Cream with Niacinamide — $13.58, 32% off:
$13.58 from $19.99. A gel-cream for oily skin that does not strip it — the combination most drugstore moisturizers get wrong.
Neutrogena Hydro Boost Hydrating Serum — $12.31, 54% off:
Over half off $26.79, and 9,000 sold last month. Hyaluronic acid at the price of a sandwich.
Aveeno Positively Radiant Face Moisturizer — $12.57, 49% off:
Down from $24.72. Soy complex and SPF, so it covers the morning step in one bottle.
Good Molecules Gentle Retinol Cream — $5.76, 28% off:
The cheapest thing on this page at $5.76, down from $8. A gentle formulation, which is the right place to start if you have never used retinol.
How to claim these amazon prime day deals:
No codes on this list — every price is a straight markdown already live at Amazon. If you normally copy codes from our Amazon promo codes hub, this one skips that step.
- Open the pair you want on Koupon.ai and tap Get deal on Amazon.
- Pick your size and colorway on the Amazon page — the discount is tied to the specific colorway, so check the price after you switch.
- Add to cart and check out. No code needed; the markdown is already applied.
🔹 Pro Tip: do not start vitamin C and retinol in the same week. Introduce one, give your skin two weeks, then add the other on alternate nights. Both are on sale here, but buying both does not mean using both from day one.
Which skincare deal saves you the most:
On percentage the medicube ampoule wins at 68% off. On dollars it is either La Roche-Posay serum at $13 off. But the honest answer is the CeraVe vitamin C at $20.65 — it outsold everything else four to one last month, and a 29% cut on the bottle people already wanted beats a 68% cut on one they are trying for the first time.
Why skincare moves before Prime Day, not during:
Prime Big Deal Days opens 6 October. Skincare is a restock category rather than an impulse one — people buy when the bottle runs out, so the popular SKUs sell through in the run-up and the ones still discounted on the day tend to be the shades and formulations nobody reached for. Everything here is live now.
For more verified amazon prime day deals like these, browse the Prime Big Deal Days hub or most-loved Amazon Prime Day deals, and get the Koupon app for alerts when a bottle restocks. These amazon prime day deals are re-checked daily.
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